Inkaterra Reserva Amazonica

Forty-five minutes upriver from the port, this eco-lodge sits deep in the Peruvian Amazon, accessible by boat and not much else. The thirty-five cabañas lean rustic-luxe, and the Canopy Tree House puts you ninety feet above the jungle floor, which either sounds thrilling or explains why there's a ground-level bedroom attached. The excursions along Madre de Dios and the trail systems are the real reason people make the trip; the comfort is a bonus.