Nueve 25 Hotel Boutique

The name is a nod to sterling silver, which requires 92.5% purity and once made this city obscenely rich. This boutique hotel in Guanajuato's UNESCO historic center sits in a restored colonial building where exposed stone walls and beamed ceilings meet contemporary styling without apology. The rooftop bar frames a skyline of antique bell towers at sunset, and the wine cellar occupies the building's original cisterns. It holds a Michelin Key.