Alchymist Grand Hotel and Spa

Casanova's ghost would feel right at home here, which either sells you or doesn't. This lavish Baroque hotel in Malá Strana tucks 26 rooms and 19 suites between Prague Castle and Petřín Hill, each dressed in gilded filigree, crystal chandeliers, antique furnishings, and hand-painted wallpaper that suggests an Italian princess briefly stepped out. The Gothic cellars beneath it all house an Indonesian-inspired spa, which is exactly the kind of left turn a hotel like this earns.