Four Seasons Hotel Philadelphia at Comcast Center

The infinity pool on the 57th floor doesn't drain into the city below, though it looks like it might. This Four Seasons occupies the top twelve floors of Philadelphia's tallest tower, which means the views from your room stretch across the whole skyline. Norman Foster designed the building, and the hotel itself plays the warm-modernist card well, with light bouncing through mirrors and enormous arrangements of flowers softening all that glass. It holds a Michelin two-key designation and a Forbes Four Star rating.