Vedema, a Luxury Collection Resort

Converted from a 15th-century winery, this five-star resort in the quieter medieval village of Megalohori trades caldera views for vineyards, courtyards, and a pace that doesn't require elbowing past tour groups. White villas, spare furnishings, and generous sitting areas make up the rooms. The wine cellar runs regular tastings, and the Canava Wine Bar, two restaurants, and an Elios spa mean staying put feels less like a compromise and more like the plan all along.